This dataset includes 10X Cell Ranger 3.1.0 outputs for each individual sample. The Cellranger pipeline produces two types of feature-barcode matrices in a sparse matrix format (matrix.mtx.gz file). The unfiltered matrix contains both background and cell-associated barcodes and filtered matrix contains only cellular barcodes. Additional files (features.tsv.gz, barcodes.tsv.gz) contain feature and barcode sequences corresponding to row and column indices in the matrix respectively. For more details see https://support.10xgenomics.com/single-cell-gene-expression/software/pipelines/3.1/output/matrices Each sample is named in the following format: patientID_condition_tissue patientID = 4-digit identifier used throughout the manuscript condition = mCRC: metastatic colorectal cancer, normal_liver: paired normal liver, PBMC: peripheral blood mononuclear cells. For more details, refer to Table 1 in the manuscript.